Sunday, December 30, 2012

Choose your car insurance option wisely | Cheap Auto Insurance

?Choose your car insurance option wisely

?Having a car simply means that you must have a car insurance coverage to protect yourself while on the road. However, with so many car insurance options available today, most car insurance policy buyers are not just confused but also find the options to overwhelming for them to make an informed choice. Things even gets trickier when the car owner gets to negotiate for insurance deductibles with the insurer career and even how much coverage is enough for his or her coverage needs. This can even be worse if you are new in the industry as shopping for the right cover is pretty hard. However, if you are facing such problems in your insurance life, you definitely do not have to worry so much as there are some guidelines to help you choose the best plan for you.

??????? First, knowing how much car insurance coverage you need is the most important thing towards choosing the best car insurance option. The value and cost of your car will play a major role in determining the amount of cover that is enough to cover you completely. If you are a teen driver, then you need to remember that your coverage plan will obviously be more expensive and you need to beware of this right from the word go.

??????? Determine your deductibles: choosing the best coverage for you requires that you are aware of the amount of deductible that is good for you. Whereas you might be tempted to opt for a higher deductible to lower your insurance cost, you also need to ensure that you will afford to pay such deductibles in case an accident happens.

??????? Examine your driving history: your driving record is a great determinant of the coverage plan suitable for you when shopping for a cover. If you had received some speeding tickets or had been involved in an accident in the past, you need to clear this with the state Department of Motor Vehicles to ensure that they do not get to disadvantage you as you search for a good plan.

??????? Search for cheap quotes: here, you need to start using the internet to shop for an affordable insurance plan from a reputable provider.

??????? Review your coverage contact: one of the biggest mistakes that car insurance buyers make is failing to review the contract before signing. However, if you need to be on the safe side, always ensure that you are really satisfied with the agreement before becoming a signatory to it.

Source: http://www.carinsurancenets.com/choose-your-car-insurance-option-wisely/

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Saturday, December 29, 2012

Honour for Higgs boson physicist

Physicist Peter Higgs, after whom the Higgs boson particle is named, has been recognised in the New Year Honours.

In the 1960s, Prof Higgs and other physicists proposed a mechanism to explain why the most basic building blocks of the Universe have mass.

The mechanism predicts the existence of a Higgs particle, the discovery of which was claimed this year at the Large Hadron Collider.

Prof Higgs has been made a Companion of Honour.

The recognition confers no title but is restricted to a select group of 65 for achievements in the arts, literature, music, science, politics, industry, or religion.

His discovery announced in July this year of a particle consistent with the Higgs boson immediately led to calls for the 83-year-old to be knighted.

He is now also considered to be a candidate for a Nobel prize, perhaps in conjunction with other physicists who reached similar conclusions at the same time.

Born in Newcastle upon Tyne, Higgs was inspired at school by the work of physicist Paul Dirac, who helped lay the foundations of quantum mechanics and predicted the existence of antimatter.

After obtaining his PhD from King's College London, he held academic positions at the University of Edinburgh and then London before returning to the Edinburgh to lecture at the Tait Institute of Mathematical Physics.

According to one popular version of the story, Prof Higgs came up with the concept during a walk in the Cairngorms. But in an interview earlier this year, he told BBC News that there was no "eureka moment".

Best explanation of Higgs boson? Continue reading the main story

The Higgs mechanism explains why the building blocks known as elementary particles have mass. According to the idea, these particles acquire mass through their interaction with a field that permeates space.

The theory predicts the existence of a new particle, which also carries Prof Higgs' name. But six physicists - including Higgs - are now generally credited with the formulation of the concept.

The idea initiated a decades-long effort to detect the particle in experiments. However, it remained elusive until this year, when scientists at the $10bn LHC particle smasher announced that they had found a particle consistent with the Higgs boson.

The probable discovery added a final missing piece to the framework known as the Standard Model, which stands as the most widely accepted theory to explain how particles of matter interact.

At the time of the announcement, Prof Higgs told reporters: "It's very nice to be right sometimes."

He added: "At the beginning I had no idea whether a discovery would be made in my lifetime because we knew so little at the beginning about where this particle might be in mass, and therefore how high an energy machine would have to go before it could be discovered.

"It's been a long wait but it might have been even longer, I might not have been still around."

Shortly after the boson news this year, Edinburgh University, where Higgs is an emeritus professor, announced a new centre that would carry his name. The Higgs Centre for Theoretical Physics will be housed at the university's James Clerk Maxwell Building.

The particle earned a nickname - the "God particle" - supposedly because of its importance to the Standard Model. But Prof Higgs stated that he disliked the term because it "might offend people who are religious".

This week, in an interview with the Spanish newspaper El Mundo, Prof Higgs criticised fellow academic - and staunch atheist - Richard Dawkins for his stance towards religious believers.

Prof Higgs said: "What Dawkins does too often is to concentrate his attack on fundamentalists. But there are many believers who are not fundamentalists. Fundamentalism is another problem. I mean, Dawkins in a way is almost a fundamentalist."

Also honoured are Sue Gibson, professor of chemistry at Imperial College London, who is becomes an OBE; Prof Richard Holdaway, director of RAL Space, which helps co-ordinate civil space activities, who becomes a CBE; and Carol Vivien Robinson, professor of chemistry at the University of Oxford, who is made a Dame.

Paul.Rincon-INTERNET@bbc.co.uk

Source: http://www.bbc.co.uk/news/science-environment-20855404#sa-ns_mchannel=rss&ns_source=PublicRSS20-sa

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Healthy Smile with Cheap Dental Plans in California | ArticlePDQ.com

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Source: http://articlepdq.com/health-fitness/medicine/healthy-smile-with-cheap-dental-plans-in-california/

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Friday, December 28, 2012

Self Improvement And Empowerment Blog: How to Stop Feelings of ...

I seek strength, not to be greater than another, but to fight my greatest enemy, the doubts within myself. ~P.D. Cast

Of all the elements that form the comfort zone, unworthiness is without question the most insidious.

Unworthiness is that shadowy deep-seated belief that creeps into our minds and tells us we are undeserving and not good enough, inadequate and fundamentally flawed. Unworthiness serves as a shield to insulate us from risk, chance and the unknown.

Some of us may already be aware of certain limiting and negative beliefs we have about ourselves. These we can learn to heal and change. The real problem goes deeper? it?s the unconscious self-doubt and unworthy feelings we accept about ourselves.

The unworthiness mantra is ?Don?t try it, don?t even think about it.?

Without realizing it, we allow unworthiness to sabotage us in a hundred different ways, using endless justifications to keep from reaching for our dreams. For the sake of shielding ourselves from even the remote possibility of having to face our own fundamental inadequacy? we will do whatever it takes to just not think about it.

We repeatedly second guess our choices; falling into endless mental reruns picking apart what we could or should have done differently; over time finding it harder and harder to make definitive decisions that will enable us to move forward.
We avoid testing (or exposing) ourselves by allowing days, weeks and years to go by as we focus on the daily minutia of life and tell ourselves we?ll get to the big important stuff as soon as we?re ?caught up? or when the ?time is right.?
We use our responsibilities, especially to others, as shields to prevent ourselves from trying something new.

While there?s a lot to be said for gratitude, there is a BIG difference between appreciating all the good things and people in your life and choosing to settle for less because you don?t believe you deserve or are capable of more.

A few months ago I received a heartbreaking note from a reader who wanted to share with me why she had just unsubscribed from IGG. She went on to explain that while she enjoyed the articles and found them inspiring they also depressed her because she found herself focusing on all that she could never have or be in her life. ?A lot of people have it worse than me, so I just need to stop dreaming and be grateful for what I have now.?

How to Resolve Feelings of Unworthiness

Be willing to challenge beliefs about yourself: Begin by exploring the ?why? behind negative self talk. Make a positive statement about yourself such as I am a loving person or I deserve to achieve my dream of (fill in the blank). Then focus on any negative or contradictory thoughts that pop into your mind about your declaration. A personal journal is a great tool for this exercise. The more specific you can be with your statement, the greater the likelihood you?ll be able to uncover those sneaky unworthy feelings.

One step at a time: Once you begin to identify unworthy thoughts or triggers you can start gently stretching the limits of your comfort zone. Be willing to try different strategies and don?t be discouraged if you have to keep at it for awhile. These feelings of unworthiness have likely been with you for decades, so be kind to yourself, celebrate small victories, and be patiently persistent.

Let go of the past: For some reason, at some point in your life you came to the conclusion that you were lacking. Maybe you were bullied as a kid, or maybe you made a mistake? maybe it was a real whopper of a mistake and now you?re stuck mentally rerunning the experience and what you could or should have done differently. It?s time to let it go. The longer this has been going on the tougher it will be to clear it from your mind, but meaningful change always begins with a decision and in this case it?s up to you to choose not to give those thoughts the energy they require to remain an active part of your life.

Risk change: The thing about unworthiness is over time it becomes a comfortable companion and it is awfully tempting to stay with what?s known rather than risk the discomfort of change, rejection or even failure. Focus on your dreams and find a purpose that is important enough to motivate you to muster the strength and courage to step into the unknown and be free of what?s holding you back.

Be willing to ask for help: Sometimes feelings of unworthiness stem from a major life change or a traumatic event. As valuable as self-directed personal growth exercises can be, it?s important to understand that asking for help is not a weakness. Even the most courageous and successful people from time to time need a helping hand to move forward.

Sometimes the space between where you are and where you want to be can feel like a massive distance, but the truth is even the most self-confident among us will experience doubt from time to time. We may not be able to completely avoid it, but we can become more resilient by developing a strategy that enables us to effectively conquer feelings of self-doubt and unworthiness. Providing useful self development, self empowerment and self esteem tips and reviews online.

Source: http://selfimprovementandempowerment.blogspot.com/2012/12/how-to-stop-feelings-of-unworthiness.html

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Source: http://foegafsad.posterous.com/self-improvement-and-empowerment-blog-how-to

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Source: http://ucotodavi.wordpress.com/2012/12/27/self-improvement-and-empowerment-blog-how-to-stop-feelings-of/

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Source: http://tatolutym.posterous.com/self-improvement-and-empowerment-blog-how-to

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HTC HD2 runs Windows RT, postpones trip to afterlife yet again

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HTC's HD2 may have begun life as just another Windows Mobile 6.5 handset, but its surprisingly hardy internals enable it to run almost any mobile OS going. The latest software to appear on the three-year-old device is Windows RT, which was jammed onto the system by a developer called Cotulla -- who previously put Windows Phone 7 on the same unit. While we imagine it's not that comfortable to use on the HD2's 4.3-inch screen, we can imagine some superheroes are now scouring eBay for a similarly immortal smartphone.

[Image Credit: Cotulla]

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Via: GSM Arena

Source: Cotulla (Twitter), (2), (3)

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/yTW2UD_ul5Y/

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Newtown Scam Arrest: Nouel Alba Busted For Starting Bogus Funeral Fund

Source: http://www.thehollywoodgossip.com/2012/12/newtown-scam-arrest-nouel-alba-busted-for-starting-bogus-funeral/

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Thursday, December 27, 2012

subedarruhit: Declining Health And Fitness: Mind Body Spirit Short ...

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Source: http://subedarruhit.blogspot.com/2012/12/declining-health-and-fitness-mind-body.html

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Kresta In The Afternoon: Why ?Gay Marriage? is Not Inevitable

marriage_dictionary

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Election Day was a drubbing for marriage. The ballot initiatives to protect marriage lost by over 4% in Maine, Minnesota, Washington State, and Maryland. Those who support same-sex ?marriage? reportedly spent over $33 million, while those who defend marriage spent just over $10 million.

Many friends have said that same-sex marriage is inevitable. It is not. I have confidence that fence-sitters will enter the fray in support of traditional marriage. As we continue to debate this issue, three important forces can shift the outcome in favor of marriage as the union of one man and one woman. Consider first, public opinion; second, the methods and the message of LGBT activists; and third, reality.

Public Opinion Gives Marriage a Fighting Chance
The American public offers differing levels of assent to same-sex marriage, depending on how the survey questions are worded. Psychologically, it matters how questions are asked.
Consider these facts:
1. Data from the New Family Structures Study (NFSS) shows 24% of the young-adult population on the fence, saying they?re ?not sure? when asked whether ?it should be legal for gays and lesbians to marry in America.? There?s more support than antagonism, but not a majority on either side, given the nearly one-quarter who remain on the sidelines.
2. A national post-election survey conducted on Election Day by The Polling Company, Inc., showed that 60% of American voters agree that ?marriage is between one man and one woman,? while only 34% disagree. Another poll two months earlier showed that 57% were in agreement.
3. After their Election Day victories, same-sex marriage advocates stated that they will continue to prioritize expanding the legal recognition of same-sex relationships as marriages through legislatures and the courts, not through public vote. This is a continuation of their past policy that avoided putting the issue up for a direct citizen vote (the ballot initiatives in Maryland, Washington, and Minnesota were initiated by supporters of traditional marriage; only Maine was their choice to repeal our side?s ballot measure of 2009). This indicates their lack of confidence in their ability to get enough votes.
4. Six New York state senators were ousted from office after they abandoned their constituents to vote in favor of same-sex marriage. Five of those senators lost their re-election bids this year, in large part due to their change of position on marriage; the sixth retired rather than face re-election.
5. ?Third Day,? a Democratic organization?s own survey revealed that on a scale of 0 ? 10, with 10 being the most in favor, 26% labeled themselves 9 ? 10 in favor of same-sex marriage, compared to 30% who said they were 0 -1; 44% were somewhere in the middle. Only 32% said they would be glad if same-sex couples could marry; 37% said that would not be acceptable.
Despite large sums spent?as happened this November when gay activists spent a whopping $33 million?the notion that marriage is between a man and a woman continues to hold sway; and, no matter how hard activists try, it seems impossible to strip it away from the human heart of a very substantial portion of people. It is the reality of common sense deeply embedded in the human heart.

Methods and Message
Efforts by the LGBT movement to make school curricula more sympathetic to the gay agenda continue to raise concerns among parents. So much so that leaders of the LGBT movement have had to adjust. In the November 7 article in Slate, titled ?How Marriage Finally Won at the Polls,? Nathaniel Frank explains how the coalition of LGBT activists working to pass gay marriage in Maine and Maryland revised their message strategy to counter the ?Princess? ad prepared by Frank Schubert. Here is what Nathaniel Frank writes:

Thalia Zepatos of Freedom To Marry, who oversees the coalition?s messaging research, describes another revelation from the data. Schubert?s misleading ?princess? ads implied that schools could usurp the role of parents in teaching pro-gay values, but that was wrong. As Zepatos and her team pored over the research, they watched conversations in which voters spoke among themselves and kept circling back to the same insight: Parents are the parents, and they teach their kids values at home. The challenge, Zepatos and her colleagues determined, was to reassure voters about this conclusion. Parents knew they had the control, but the Schubert ads?which in the past have killed a pro-gay lead in the polls at the last minute?made them anxious about losing it.
LGBT activists have had to go out of their way to reassure parents they are in charge of teaching values to their children, given the powerful evidence provided by Schubert, and experienced by many parents.
A 2011 Research Report issued by the Democratic think tank Third Way, and used to develop the 2012 campaign to win the state ballot initiatives, stated among its six key findings that: ?It is crucial to include reaffirmation of religious liberty protections as a significant part of supporters? message framework.? And as the public is aware, it is increasingly being proclaimed by politicians working to pass gay marriage that religious liberty protections are being provided.
But this is misleading. As Jane Robbins and Emmett McGroarty show in their Public Discourse article ?Mandating Our Religious Freedom,? the current Progressive movement, of which LGBT activists are a core constituency, is clearly moving in the opposite direction. And in a more recent Public Discourse article ?A War on Religion?? Bruce Hausknecht provides examples contrary to the message LGBT leaders are now using to win.

Reality: Distinguishing What Is Myth from What Is True
The Left now has the White House (for four more years), in addition to the universities, Hollywood, large portions of the media, and high-tech industry.
But can this reliance on the power of the elite institutions be sustained in the long run? Perhaps, if the majority of the people come to accept that to flourish one is to be allowed to do whatever one wants regarding sexual practices. I submit that the majority of people do not grasp that this is the message of the LGBT movement, and as they do grasp it, they will shift to the view that our sexuality has boundaries and is ordained toward something greater than whatever we want.
Don?t take it from me; take it from Dan Savage as quoted by Mark Oppenheimer?s New York Times article, ?Married with Infidelities?:

Savage believes monogamy is right for many couples. But he believes that our discourse about it, and about sexuality more generally, is dishonest. Some people need more than one partner, he writes, just as some people need flirting, others need to be whipped, others need lovers of both sexes. We can?t help our urges, and we should not lie to our partners about them. In some marriages, talking honestly about our needs will forestall or obviate affairs; in other marriages, the conversation may lead to an affair, but with permission. In both cases, honesty is the best policy.
Social science research shows us, and a growing body of journalistic reporting reveals, that gay men are not interested in permanent monogamous relationships. Lesbians are more apt to be monogamous, but less apt to remain together long-term. One myth that LGBT activists push is that marriage is what most homosexual people want. Will the provision of marriage cause gay and lesbian Americans to enter lasting and stable relationships en masse? Unlikely. Another myth that the activists push is the ?no differences? thesis: the claim that there are no differences in outcomes for children parented by heterosexual couples or homosexual couples.
The sonogram helped people see the unborn child in the womb and realize it is alive; it made a powerful case for life. Similarly, we have to expose the myths of the gay marriage movement. Several events of 2012 have brought us closer to that goal.
First, in a peer-reviewed research paper published in the prestigious journal Social Science Research, titled ?Same-sex parenting and children?s outcomes: A closer examination of the American psychological association?s brief on lesbian and gay parenting,? Professor Loren Marks of Louisiana State University?s School of Human Ecology reviews the 59 studies referenced in the 2005 American Psychological Association brief that supported the ?no differences? thesis. Marks concludes:
To restate, not one of the 59 studies referenced in the 2005 APA Brief compares a large, random, representative sample of lesbian or gay parents and their children with a large, random, representative sample of married parents and their children. The available data, which are drawn primarily from small convenience samples, are insufficient to support a strong generalizable claim either way. Such a statement would not be grounded in science.
Second, Mark Regnerus?s New Family Structures Study (NFSS) uses the second-largest nationally representative sample (ever) to measure a host of outcomes in which the adult children of intact biological families fare better than any other combination, including children raised by a mother or a father who has been in a gay or a lesbian relationship. Its results also show something striking and unexpected: only two out of 15,000 young Americans screened for the survey reported spending their entire childhood with two lesbian parents; none reported the same with two gay fathers. Children, of course, don?t fare as well when there is a lack of stability in the home.
Third, scores of people who read the Regnerus study were inspired to reveal even more about the gay subculture; and, yes, by their accounts, the Regnerus study depicts reality far better than shows like Modern Family and The New Normal. Surprised? Most of these people will remain nameless, rather than submit themselves to unwanted hostility. But expect more of them to step up as witnesses to the lies that undergird the movement for same-sex marriage. See, for example, Robert Lopez?s essay ?Growing Up With Two Moms: The Untold Children?s View.?
Fourth, legal cases are mounting against the discrimination, harassment, and loss of jobs for people who do not support same-sex marriage. A new growth industry is the pro bono legal associations to protect freedom of conscience and freedom of religion, such as the Alliance Defending Freedom, the Becket Fund for Religious Liberty, and more recently the newly created Freedom of Conscience Fund. It is very laudable that trained professionals are stepping up to defend civil liberties; one may hope this will continue to awaken the conscience of the public.
Ultimately, the future of marriage will not be decided by our likes or our dislikes. Human suffering will periodically remind us that losing a healthy marriage culture produces all kinds of practical costs and penalties. These are measured by those social pathologies that impose a great weight on our society, such as depression, addiction, violence, and illness, as well as missed educational and economic opportunities. However you slice it, the intact biological family continues to be the best ?Department of Health, Education and Welfare? when it comes to raising the next generation. Marriage is worth fighting for, even if we lose. Because remember, LGBT activists will lose too as they bring us all down. And that is a sobering thought.
This essay first appeared November 26, 2012 on Public Discourse, the online journal of the Witherspoon Institute, and is reprinted with permission.

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Source: http://krestaintheafternoon.blogspot.com/2012/12/why-gay-marriage-is-not-inevitable.html

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The end of One London Bridge ? and the end of London Bridge itself ...

Old London Bridge, courtesy of Motco, with the site of my ancestor?s house at One London Brige arrowed in red.

In the second half of the 18th Century my family lived at One London Bridge ? the first house and shop you came to as you entered the City of London? from the Southwark end. One of the things which I find incredibly sad about the family diaries from the 18th and 19th Centuries is the story of Francis Hall (the younger of two sons which my 4xgreat grandfather had by his first wife). After all, he never really wanted to be a shopkeeper ? he was never trained as a haberdasher like his father and elder brother, and was only drafted in to the family business at Number One London Bridge when brother William got bored with the retail trade and deserted the shop for the freedom of being a silk-man. That was in the 1790?s.

Francis stepped into the breach without complaint. His life wasn?t easy ? his first wife died in 1799 shortly after giving birth to a son. Her previous pregnancies had resulted in three live births (all three of them boys and all three of them dying within a couple of months) and a pair of stillborn twins. She was just 28 at the time of her death, which resulted from complications linked to the birth, but the latest child, another boy, somehow survived.

Bringing up a tiny infant while trying to run the business must have been a daunting task for the newly widowed Francis ? it doesn?t bear thinking about! In practice he married again fairly soon afterwards, but never had any more children.

From the moment when he became an owner of the business (jointly with father Richard, who took no part in the running of the shop, but who paid all the bills and pocketed half the profits) Francis knew that he was in charge of an asset which had a declining value as the lease ran out. Richard had originally signed a 61 year lease from the Corporation of London at an annual rent of just under ?28. It would inevitably expire on Christmas Day 1826, at which point Francis would have to move out and surrender possession to the Landlord. He must have felt the clock ticking every day, especially after his father died in 1801 leaving him the business. He would know full well that he would be 68 years old when the lease expired ? and he would be losing not just his business but?the?home? he had lived in since he was twelve years old as well.

There was something else looming over Francis ? the knowledge that all he had worked for, all he had done, was likely to be pulled down as soon as the lease was up. He would have known that plans had been mooted from the very beginning of the century to pull down the old bridge and put up a new one just upstream? and that the building at One London Bridge would be demolished so that improved access roads could be constructed. Year by year the knife would have been driven home ? a competition to find the best design, parliamentary approval, detailed feasibility studies etc.

All the time the old bridge was deteriorating. The Great Arch had been constructed?only seventy years earlier?but the?pillars were all constructed on their original 500 year old foundations and they were beginning to suffer subsidence. Bluntly the bridge was no longer fit for purpose ? either for shipping or for pedestrians, let alone for vast numbers of carts carriages and wheeled vehicles, livestock and so on.

Rennie?s design for the new bridge showing the old bridge with its many arches and starlings.

In July 1823 Parliament finally authorised work to commence in accordance with the plans prepared by John Rennie. The first pile was driven on March 15th 1824 and a year later, on 15th June, the foundation stone was laid with great ceremony.

All day and every day Francis Hall would have had to contend with the noise and dust of construction work, especially with constant pile driving. It can hardly have been conducive to the business of selling fabrics and general haberdashery! To add to his misfortunes his second wife died in July 1825. By then his son had grown up and left home, so Francis would have been alone in the house in those final years.

The view from Francis Hall?s window, showing the new bridge on the right

The warehouse premises next door to Number One were pulled down, and Francis would have had a grandstand view from his living room window of the coffer dam being built to his right, and the excavation for a grand flight of steps leading to the water?s edge, immediately in front of him. The old bridge to the left was still in use, but shored up in places with wooden boards to try and stop any more masonry falling into the river.

Close up view of the starlings? beneath the old bridge, with St Magnus the Martyr in the background.

The excellent map by Greenwood dated 1827 shows the two bridges side by side, and I have highlighted in red the building where Francis would have watched the unfolding picture.

The stone blocks for the new bridge were cut and the arches laid out on the Isle of Dogs, and then lettered and numbered before being brought to the site and lowered into place. Everywhere cranes and derricks were loading and unloading, while stone-masons hammered away. Men swarmed over the scaffolding like ants.

The view towards the site of One London Bridge showing the lower half of the Monument in the background.

December 1826 must have been especially poignant for Francis as he found buyers for his remaining stock within the trade, and began plans for moving out. Maybe he over-did the furniture shifting. Or maybe he simply was heart-broken to be leaving ? either way, the lease expired on Christmas Day, and Francis, whose birthday it was on Boxing Day,?expired immediately afterwards.

This painting from 1827 looking at the Northern bank of the river from the Southwark side,?shows the old bridge on the right, and is looking straight at the site of One London Bridge, It is low tide and the starlings supporting the pillars of the old bridge are exposed. The parapet above the fifth arch is shored up, and the subsidence in the old arches is clearly visible. Standing above the line of the parapet can be seen a number of the cupulas, designed to give shelter and protection to pedestrians, mentioned below.

Francis never saw the New Bridge being formally opened on the 1st of August, 1831, in the presence of His Majesty King William IV. The picture above (courtesy of the Tate) shows the opening ceremony with the old bridge in the background ? demolition could not start in earnest until the new structure was fully operational

He?never got to see the old bridge being pulled down arch by arch, and the old starlings, used to protect the foundations, being excavated and removed. Today very few pieces of stonework remain ? although there are a couple of the old cupolas? to be found in Victoria Park.

?

What is especially interesting is the incredibly detailed record of the works as they progressed, drawn by a young man called Edward William Cooke. He started his drawings in 1826 when he was fifteen. Guildhall Library holds 69 of these drawings: according to their site they were presented in 1872 by Alderman Sir David Salomons, a close friend of Cooke. Twelve of the drawings were later selected for engraving and publication in 1833 under the title ?Views of the Old and New London Bridge?

Here is his?picture of the demolition of one of the pillars to the Great Arch:

Within a few years no trace remained of the old bridge, and the old family shop at Number One passed into history. But I do rather like this 1870?painting of the Rennie bridge, looking towards where the family ran their business for over 60 years. It is shown courtesy of the Atkinson Grimshaw website at http://www.johnatkinsongrimshaw.org? :

?

Source: http://blog.mikerendell.com/?p=4736

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Monday, December 24, 2012

Patch Recipes: Drink it up on Christmas ? Patch.com

Patch Recipes: Drink it up on Christmas ? Patch.com

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December 22, 2012. Posted 3 hours ago.Posted in: Drink Recipes
Patch Recipes: Drink it up on Christmas
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Source: http://www.foodanddrinktips.com/patch-recipes-drink-it-up-on-christmas-patch-com/27251

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Source: http://writingandspeaking.deadale.com/uncategorized/tips-you-may-not-know-about-article-marketing/

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Three new genetic links to colorectal cancer

Dec. 23, 2012 ? Vanderbilt-Ingram Cancer Center investigators have identified three new genetic "hotspots" linked to colorectal cancer.

These variants, reported Dec. 23 in an Advanced Online Publication in Nature Genetics, provide new insight into the biology of colorectal cancer -- and could represent new therapeutic targets for the disease.

Colorectal cancer is one of the most commonly diagnosed cancers worldwide -- and rates are particularly high in the United States and other developed countries. Genetics plays an important role in both sporadic and familial (inherited) forms of the disease. However, only about 6 percent of colorectal cancer cases are explained by the rare genetic variants known to confer high risk of colorectal cancer (as seen in familial forms of the disease).

Previous studies on the genetic basis of colorectal cancer have pinpointed several additional variants, but most of the studies were conducted in European/Caucasian populations.

"Looking at different ethnic groups is important because the genetic structures can be different enough that variants identified in one population do not explain risk in other populations," said Wei Zheng, M.D., Ph.D., MPH, an Ingram Professor of Cancer Research and senior author on the study. "Because of the difference in genetic structures and underlying environment exposures, it might be easier to discover some risk variants in studies conducted in non-European populations."

In 2009, Zheng and colleagues in several Asian countries established the "Asia Colorectal Cancer Consortium" to search for novel genetic risk factors for the disease. The consortium included populations in China, Korea and Japan.

Using an approach known as a "genome-wide association study" (or GWAS), Zheng and colleagues began searching for common variants linked to disease risk.

From genomic data obtained from 2,098 colorectal cancer cases and 5,749 controls, the researchers identified 64 variants, or "single nucleotide polymorphisms" (SNPs), that were associated with colorectal cancer.

The investigators then replicated these findings in another set of samples, narrowing down the number of disease-associated variants to four. Three of those four variants were also associated with colorectal cancer risk in a larger European sample.

"The findings from this study are relevant to both Asian and European populations," said Zheng. "Interestingly, these three susceptibility loci were not discovered in previous studies conducted in European-ancestry populations."

This study highlights the importance of conducting genetic studies in non-European populations to fully uncover the genetic basis for common diseases, including colorectal cancer, Zheng noted.

While the specific functions of these newly identified susceptibility loci are not clear yet, several important genes are located in the regions near the risk variants discovered in this study. For example, one risk variant is located near CCND2, the gene encoding cyclin D2, a member of the cyclin family of proteins that regulate the cell cycle. Cyclins have been linked to cancer, but research on the CCND2 gene has been limited. Therefore, the current findings suggest the need for further research on the role of other cyclins and cyclin-dependent kinases in carcinogenesis.

"These new discoveries are very exciting," Zheng said. "They will certainly lead to future studies regarding the biology of these regions and the translational potential of these findings in cancer prevention and treatment."

The research was supported in part by grants from the National Cancer Institute (CA070878, CA082729, CA124558, CA148667 and CA122364) of the National Institutes of Health.

Zheng is also a professor of Medicine, director of the Vanderbilt Epidemiology Center, and chief of the Division of Epidemiology at Vanderbilt University.

Other Vanderbilt authors on the paper were: Ben Zhang, Ph.D.; Qiuyin Cai, M.D., Ph.D.; Jirong Long, Ph.D.; Jiajun Shi, Ph.D.; Wanqing Wen, M.D., MPH; Gong Yang, M.D., MPH; Ryan Delahanty, Ph.D., and Xiao-Ou Shu, M.D., Ph.D.

This research was conducted in collaboration with investigators from Sun Yat-sen University Cancer Center (China), Aichi Cancer Center Research Institute (Japan), Korean National Cancer Center (South Korea), the Shanghai Cancer Institute (China), Yonsei University (South Korea), Hallym University College of Medicine (South Korea), National Cancer Institute (USA), Kyoto University Center for Genomic Medicine (Japan), and Seoul National University College of Medicine (South Korea).

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Story Source:

The above story is reprinted from materials provided by Vanderbilt University Medical Center, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Wei-Hua Jia, Ben Zhang, Keitaro Matsuo, Aesun Shin, Yong-Bing Xiang, Sun Ha Jee, Dong-Hyun Kim, Zefang Ren, Qiuyin Cai, Jirong Long, Jiajun Shi, Wanqing Wen, Gong Yang, Ryan J Delahanty, Bu-Tian Ji, Zhi-Zhong Pan, Fumihiko Matsuda, Yu-Tang Gao, Jae Hwan Oh, Yoon-Ok Ahn, Eun Jung Park, Hong-Lan Li, Ji Won Park, Jaeseong Jo, Jin-Young Jeong, Satoyo Hosono, Graham Casey, Ulrike Peters, Xiao-Ou Shu, Yi-Xin Zeng, Wei Zheng. Genome-wide association analyses in east Asians identify new susceptibility loci for colorectal cancer. Nature Genetics, 2012; DOI: 10.1038/ng.2505

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/iZRRoxpFSzA/121223152624.htm

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Thursday, December 20, 2012

Feds end Southern California otter ban; expansion of range seen as key to species recovery

WATSONVILLE -- Federal authorities lifted a quarter-century no-otter zone for the waters off Southern California on Tuesday.

The end of the ban south of Point Conception extends federal protections to otters throughout their historic range along California's coast.

"Trying to tell a marine mammal to stay on one side of an imaginary line across the water was a dumb idea," said Steve Shimek, executive director of The Otter Project. The change in policy "will not only protect sea otters from harm, but because of the otters' critical role in the environment, it will also help restore our local ocean ecosystem."

Otters can migrate into the waters of Southern California without threat of being caught and returned to Northern California.

The Monterey-based advocacy group, along with the Santa Barbara-based Environmental Defense Center fought the no-otter zone in court. The 2009 settlement of the lawsuit led to Tuesday's action by the U.S. Fish and Wildlife Service after a series of hearings and an environmental review.

Some 12,000 to 16,000 southern sea otters once roamed from Oregon to Baja, Mexico, but the species was hunted to near extinction for its fur during the 18th and 19th centuries.

The no-otter zone was established in 1987, as federal authorities, worried about a catastrophe such as an oil spill wiping out the chance of a recovery for the threatened species, attempted to establish a back-up population on a remote

Channel Island.

Commercial fishing and oil interests, as well as the Navy, objected to the plan to bring otters south, where they could compete for resources and complicate offshore development. To appease opponents, federal authorities restricted otters in southern waters to San Nicolas Island.

The otters, however, ignored the rule. Those at San Nicolas refused to stay put, and the population there dwindled. Others wandered south from more northern waters.

In 2001 federal officials announced they would no longer enforce the ban, but without the legal protections enjoyed by the species north of Point Conception, otters remained at risk in southern waters. That led to the lawsuit filed by the two environmental groups, which maintain the species needs to reoccupy its historic territory to recover.

Follow Sentinel reporter Donna Jones on Twitter at Twitter.com/DonnaJonesSCS

Source: http://www.santacruzsentinel.com/watsonville/ci_22219845/feds-end-southern-california-otter-ban-expansion-range?source=rss

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Wednesday, December 19, 2012

Sudan-South Sudan oil talks break without progress

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  • Man working at Shaw AFB dies in crash

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  • News Summary: Budget-deal optimism boosts stocks

    News Summary: Budget-deal optimism boosts stocks

    By The Associated Press STEP AWAY FROM THE EDGE: More signs from Washington that policymakers are moving forward in crucial budget talks helped boost stocks. The Standard & Poor's 500...More >>By The Associated Press STEP AWAY FROM THE EDGE: More signs from Washington that policymakers are moving forward in crucial budget talks helped boost stocks. The Standard & Poor's 500 closed at its...More >>
  • How the Dow Jones industrial average fared Tuesday

    How the Dow Jones industrial average fared Tuesday

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  • Gold falls as US budget talks continue

    Gold falls as US budget talks continue

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ADDIS ABABA, Ethiopia (AP) - Officials have failed to make progress in talks that would see South Sudan resume its oil exports through Sudan.

The presidents of the two African nations sealed deals in September for a demilitarized zone between their borders and other security agreements that would allow the oil exports to resume.

South Sudan exports its oil through Sudan's pipelines, but those exports have been halted since early 2012. Sudan gets a cut of the exports' revenue.

Tuesday's meeting in Ethiopia ended without agreement on implementing September's deals.

African Union mediator and former South African president Thabo Mbeki says the two sides would meet again on the issue in January.

The leaders of Sudan and South Sudan also are scheduled to meet during a January summit in Ethiopia.

Copyright 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://www.wistv.com/story/20374999/sudan-south-sudan-oil-talks-break-without-progress

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